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Department of Urology

Mack Roach III, MD

Recent Publications

Publications – 2009

Chung, H.T., P. Xia, L.W. Chan, E. Park-Somers, and M. Roach, 3rd, Does image-guided radiotherapy improve toxicity profile in whole pelvic-treated high-risk prostate cancer? Comparison between IG-IMRT and IMRT. Int J Radiat Oncol Biol Phys, 2009. 73(1): p. 53-60.
Roach, M., 3rd, Predicting pathologic stage, nomograms, and clinical judgment: don't miss the forest for the trees! Int J Radiat Oncol Biol Phys, 2009. 73(2): p. 325-6.
Stone, N.N., L. Potters, B.J. Davis, J.P. Ciezki, M.J. Zelefsky, M. Roach, K. Shinohara, P.A. Fearn, M.W. Kattan, and R.G. Stock, Multicenter analysis of effect of high biologic effective dose on biochemical failure and survival outcomes in patients with Gleason score 7-10 prostate cancer treated with permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys, 2009. 73(2): p. 341-6.
 

Publications – 2008

Chan, L.W., P. Xia, A.R. Gottschalk, M. Akazawa, M. Scala, B. Pickett, I.-C. Hsu, J. Speight, and M. Roach, Proposed Rectal Dose for Patients Undergoing Definitive Whole Pelvic Radiotherapy for Clinically Localized Prostate Cancer. International Journal of Radiation Oncology, Biology, Physics, 2008.
D'Ambrosio, D.J., A. Pollack, E.E. Harris, R.A. Price, Jr., L.J. Verhey, M. Roach, 3rd, D.J. Demanes, M.L. Steinberg, L. Potters, P.E. Wallner, and A. Konski, Assessment of external beam radiation technology for dose escalation and normal tissue protection in the treatment of prostate cancer. Int J Radiat Oncol Biol Phys, 2008. 70(3): p. 671-7.
Hartsell, W.F., M. Desilvio, D.W. Bruner, C. Scarantino, R. Ivker, M. Roach, 3rd, J. Suh, W.F. Demas, B. Movsas, I.A. Petersen, and A.A. Konski, Can physicians accurately predict survival time in patients with metastatic cancer? Analysis of RTOG 97-14. J Palliat Med, 2008. 11(5): p. 723-8.
Joseph, T., D.A. McKenna, A.C. Westphalen, F.V. Coakley, S. Zhao, Y. Lu, I.C. Hsu, M. Roach, 3rd, and J. Kurhanewicz, Pretreatment Endorectal Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging Features of Prostate Cancer as Predictors of Response to External Beam Radiotherapy. Int J Radiat Oncol Biol Phys, 2008.
Lawton, C.A., J. Michalski, I. El-Naqa, D. Kuban, W.R. Lee, S.A. Rosenthal, A. Zietman, H. Sandler, W. Shipley, M. Ritter, R. Valicenti, C. Catton, M. Roach, 3rd, T.M. Pisansky, and M. Seider, Variation in the Definition of Clinical Target Volumes for Pelvic Nodal Conformal Radiation Therapy for Prostate Cancer. Int J Radiat Oncol Biol Phys, 2008.
Lometti, M.W., D. Thurston, M. Aubin, A. Bock, L. Verhey, J.M. Lockhart, R. Bland, J. Pouliot, and M. Roach, 3rd, Are lateral electronic portal images adequate for accurate on-line daily targeting of the prostate? Results of a prospective study. Med Dosim, 2008. 33(1): p. 22-9.
McKenna, D.A., F.V. Coakley, A.C. Westphalen, S. Zhao, Y. Lu, E.M. Webb, B. Pickett, M. Roach, 3rd, and J. Kurhanewicz, Prostate Cancer: Role of Pretreatment MR in Predicting Outcome after External-Beam Radiation Therapy--Initial Experience. Radiology, 2008.
Roach, M., 3rd, Editorial comment on: high provider volume is associated with lower rate of secondary therapies after definitive radiotherapy for localized prostate cancer. Eur Urol, 2008. 54(1): p. 105-6.
Roach, M., 3rd, "Short- and long-term mortality with localized prostate cancer": errors and omissions? Arch Intern Med, 2008. 168(12): p. 1351; author reply 1353.
Roach, M., 3rd, Targeting pelvic lymph nodes in men with intermediate- and high-risk prostate cancer, and confusion about the results of the randomized trials. J Clin Oncol, 2008. 26(22): p. 3816-7; author reply 3817-8.
Roach, M., 3rd, K. Bae, J. Speight, H.B. Wolkov, P. Rubin, R.J. Lee, C. Lawton, R. Valicenti, D. Grignon, and M.V. Pilepich, Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: long-term results of RTOG 8610. J Clin Oncol, 2008. 26(4): p. 585-91.
Roach, M., H. Chung, and J.L. Speight, Intermediate-risk and Locally Advanced Prostate Cancer, in Principles and Practice of Radiation Oncology, E. Halperin, C. Perez, and L. Brady, Editors. 2008, Lippincott, Williams and Wilkins.
Sahgal, A., S. Jabbari, J. Chen, B. Pickett, M. Roach, 3rd, V. Weinberg, I.C. Hsu, and J. Pouliot, Comparison of dosimetric and biologic effective dose parameters for prostate and urethra using 131 Cs and 125 I for prostate permanent implant brachytherapy. Int J Radiat Oncol Biol Phys, 2008. 72(1): p. 247-54.
Schroder, F.H., M. Roach, 3rd, and P. Scardino, Clinical decisions. Management of prostate cancer. N Engl J Med, 2008. 359(24): p. 2605-9.
Shinohara, K. and M. Roach, 3rd, Technique for Implantation of Fiducial Markers in the Prostate. Urology, 2008. 71(2): p. 196-200.
Taussky, D., K. Bae, J.P. Bahary, M. Roach, 3rd, C.A. Lawton, W.U. Shipley, and H.M. Sandler, Does Timing of Androgen Deprivation Influence Radiation-Induced Toxicity? A Secondary Analysis of Radiation Therapy Oncology Group Protocol 9413. Urology, 2008.
Yu, J.S. and M. Roach, 3rd, Quality of life and satisfaction with outcome among prostate-cancer survivors. N Engl J Med, 2008. 359(2): p. 200; author reply 201-2.
 

Publications – 2007

Bermudez, R.S., A. Izaguirre, and M. Roach, 3rd, State-of-the-art radiotherapy in the management of clinically localized prostate carcinoma. Future Oncol, 2007. 3(1): p. 103-11.
Frank, S.J., P.D. Grimm, J.E. Sylvester, G.S. Merrick, B.J. Davis, A. Zietman, B.J. Moran, D.C. Beyer, M. Roach, 3rd, D.H. Clarke, R.G. Stock, W. Robert Lee, J.M. Michalski, K.E. Wallner, M. Hurwitz, L. Potters, D.A. Kuban, B.R. Prestidge, R. Vera, S. Hathaway, and J.C. Blasko, Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United States. Brachytherapy, 2007. 6(1): p. 2-8.
Lawton, C.A., M. Desilvio, M. Roach, 3rd, V. Uhl, R. Kirsch, M. Seider, M. Rotman, C. Jones, S. Asbell, R. Valicenti, S. Hahn, and C.R. Thomas, Jr., An Update of the Phase III Trial Comparing Whole Pelvic to Prostate Only Radiotherapy and Neoadjuvant to Adjuvant Total Androgen Suppression: Updated Analysis of RTOG 94-13, with Emphasis on Unexpected Hormone/Radiation Interactions. Int J Radiat Oncol Biol Phys, 2007.
Lawton, C.A., M. DeSilvio, M. Roach, 3rd, V. Uhl, R. Kirsch, M. Seider, M. Rotman, C. Jones, S. Asbell, R. Valicenti, S. Hahn, and C.R. Thomas, Jr., An update of the phase III trial comparing whole pelvic to prostate only radiotherapy and neoadjuvant to adjuvant total androgen suppression: updated analysis of RTOG 94-13, with emphasis on unexpected hormone/radiation interactions. Int J Radiat Oncol Biol Phys, 2007. 69(3): p. 646-55.
Lee, B., K. Shinohara, V. Weinberg, A.R. Gottschalk, J. Pouliot, M. Roach, 3rd, and I.C. Hsu, Feasibility of high-dose-rate brachytherapy salvage for local prostate cancer recurrence after radiotherapy: the University of California-San Francisco experience. Int J Radiat Oncol Biol Phys, 2007. 67(4): p. 1106-12.
Litzenberg, D.W., T.R. Willoughby, J.M. Balter, H.M. Sandler, J. Wei, P.A. Kupelian, A.A. Cunningham, A. Bock, M. Aubin, M. Roach, 3rd, K. Shinohara, and J. Pouliot, Positional Stability of Electromagnetic Transponders Used for Prostate Localization and Continuous, Real-Time Tracking. Int J Radiat Oncol Biol Phys, 2007.
Ludlum, E., G. Mu, V. Weinberg, M. Roach, 3rd, L.J. Verhey, and P. Xia, An algorithm for shifting MLC shapes to adjust for daily prostate movement during concurrent treatment with pelvic lymph nodes. Med Phys, 2007. 34(12): p. 4750-6.
Meyer, J.L., S. Leibel, M. Roach, and S. Vijayakumar, New technologies for the radiotherapy of prostate cancer. A discussion of clinical treatment programs. Front Radiat Ther Oncol, 2007. 40: p. 315-37.
Mohler, J., R.J. Babaian, R.R. Bahnson, B. Boston, A. D'Amico, J.A. Eastham, R.J. Hauke, R.P. Huben, P. Kantoff, M. Kawachi, M. Kuettel, P.H. Lange, C. Logothetis, G. MacVicar, A. Pollack, J.M. Pow-Sang, M. Roach, 3rd, H. Sandler, D. Shrieve, S. Srinivas, P. Twardowski, D.A. Urban, and P.C. Walsh, Prostate cancer. Clinical practice guidelines in oncology. J Natl Compr Canc Netw, 2007. 5(7): p. 650-83.
Roach, M., 3rd, Dose escalated external beam radiotherapy versus neoadjuvant androgen deprivation therapy and conventional dose external beam radiotherapy for clinically localized prostate cancer: do we need both? Strahlenther Onkol, 2007. 183 Spec No 2: p. 26-8.
Roach, M., 3rd, Editorial Comment on: High Provider Volume is Associated with Lower Rate of Secondary Therapies after Definitive Radiotherapy for Localized Prostate Cancer. Eur Urol, 2007.
Roach, M., 3rd, Regarding the influence of adjuvant suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarction: how real is the risk? J Clin Oncol, 2007. 25(33): p. 5325-6; author reply 5326.
Roach, M., 3rd, M. De Silvio, T. Rebbick, D. Grignon, M. Rotman, H. Wolkov, B. Fisher, G. Hanks, W.U. Shipley, A. Pollack, H. Sandler, and D. Watkins-Bruner, Racial Differences in CYP3A4 Genotype and Survival Among Men Treated on Radiation Therapy Oncology Group (RTOG) 9202: A Phase III Randomized Trial. Int J Radiat Oncol Biol Phys, 2007.
Roach, M., 3rd and A. Izaguirre, Goserelin acetate in combination with radiotherapy for prostate cancer. Expert Opin Pharmacother, 2007. 8(2): p. 257-64.
Roach, M., 3rd, V. Weinberg, H. Sandler, and I. Thompson, Staging for prostate cancer: time to incorporate pretreatment prostate-specific antigen and Gleason score? Cancer, 2007. 109(2): p. 213-20.
Sahgal, A. and M. Roach, 3rd, Permanent prostate seed brachytherapy: a current perspective on the evolution of the technique and its application. Nat Clin Pract Urol, 2007. 4(12): p. 658-70.
Schiffner, D.C., A.R. Gottschalk, M. Lometti, M. Aubin, J. Pouliot, J. Speight, I.C. Hsu, K. Shinohara, and M. Roach, 3rd, Daily electronic portal imaging of implanted gold seed fiducials in patients undergoing radiotherapy after radical prostatectomy. Int J Radiat Oncol Biol Phys, 2007. 67(2): p. 610-9.
Speight, J.L. and M. Roach, 3rd, Advances in the treatment of localized prostate cancer: the role of anatomic and functional imaging in men managed with radiotherapy. J Clin Oncol, 2007. 25(8): p. 987-95.
Speight, J.L. and M. Roach, Radiotherapy of Urologic Tumors, in Smith’s General Urology, J. McAnnich and E. Tanagho, Editors. 2007, Lange Medical Books/McGraw-Hill.
Stone, N.N., L. Potters, B.J. Davis, J.P. Ciezki, M.J. Zelefsky, M. Roach, P.A. Fearn, M.W. Kattan, and R.G. Stock, Customized dose prescription for permanent prostate brachytherapy: insights from a multicenter analysis of dosimetry outcomes. Int J Radiat Oncol Biol Phys, 2007. 69(5): p. 1472-7.
Zapotoczna, A., G. Sasso, J. Simpson, and M. Roach, 3rd, Current role and future perspectives of magnetic resonance spectroscopy in radiation oncology for prostate cancer. Neoplasia, 2007. 9(6): p. 455-63.