Sunita Ho, MS, PhD

Dr. Sunita Ho_Sunita Ho Lab

Sunita Ho

Professor of Preventive and Restorative Dental Sciences (PRDS) and Urology

Biography

Mechanical loads manifest into strains within tissues and interfaces of an organ. Strains within tissues are transduced by the cells to produce the needed extracellular matrix proteins to meet functional demands. This is the general philosophy of research in my laboratory which is within the Division of Biomaterials and Bioengineering. Our lab has a strong focus on mechanics, materials, and investigating adaptation of tissues/interfaces through spatiotemporal mapping of “mechano-responsiveness”. This is done by correlating mechanical strain induced biochemical signals at soft-hard tissue interfaces using several model systems including the bone-ligament-tooth fibrous joint.

Due to the interdisciplinary nature of research, my laboratory is extended to the Molecular Foundry of Lawrence Berkeley National Laboratory, and Stanford Synchrotron Radiation Lightsource (SSRL) at Stanford Linear Accelerator Center (SLAC) with the help of NIH and DOE funded/peer-reviewed proposals. Mapping of biochemical expressions, physical properties of load bearing tissues, and biomechanics of organs are performed at UCSF, and as a guest scientist at the national laboratories/facilities.

Research Interests

June 19, 2020 - June 22, 2023 - Functional Competance of Dentoalveolar Joints in Vertebrates , Principal Investigator . Sponsor: NIH/NIDCR, Sponsor Award ID: 2 R01 DE022032 06A1

July 11, 2016 - June 30, 2019 - Multiscale form and function can predict renal biomineralization , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21DK109912

February 9, 2012 - January 31, 2017 - Load-mediated Adaptation of the Bone-PDL-Tooth Complex in Vertebrates , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DE022032

March 1, 1980 - February 28, 2015 - A Synchroton Radiation Structural Biology Resource , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P41RR001209

July 1, 2008 - June 30, 2012 - Biomimetic Properties of Cementum and Its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R00DE018212

July 15, 2010 - July 14, 2011 - High Resolution Non-Invasive Imaging of Oral and Craniofacial Tissues , Principal Investigator . Sponsor: NIH, Sponsor Award ID: S10RR026645

July 1, 2007 - June 30, 2008 - Biomimetic Properties of Cementum and its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K99DE018212

June 19, 2020 - June 22, 2023 - Functional Competance of Dentoalveolar Joints in Vertebrates , Principal Investigator . Sponsor: NIH/NIDCR, Sponsor Award ID: 2 R01 DE022032 06A1

July 11, 2016 - June 30, 2019 - Multiscale form and function can predict renal biomineralization , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21DK109912

February 9, 2012 - January 31, 2017 - Load-mediated Adaptation of the Bone-PDL-Tooth Complex in Vertebrates , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DE022032

March 1, 1980 - February 28, 2015 - A Synchroton Radiation Structural Biology Resource , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P41RR001209

July 1, 2008 - June 30, 2012 - Biomimetic Properties of Cementum and Its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R00DE018212

July 15, 2010 - July 14, 2011 - High Resolution Non-Invasive Imaging of Oral and Craniofacial Tissues , Principal Investigator . Sponsor: NIH, Sponsor Award ID: S10RR026645

July 1, 2007 - June 30, 2008 - Biomimetic Properties of Cementum and its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K99DE018212

June 19, 2020 - June 22, 2023 - Functional Competance of Dentoalveolar Joints in Vertebrates , Principal Investigator . Sponsor: NIH/NIDCR, Sponsor Award ID: 2 R01 DE022032 06A1

July 11, 2016 - June 30, 2019 - Multiscale form and function can predict renal biomineralization , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21DK109912

February 9, 2012 - January 31, 2017 - Load-mediated Adaptation of the Bone-PDL-Tooth Complex in Vertebrates , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DE022032

March 1, 1980 - February 28, 2015 - A Synchroton Radiation Structural Biology Resource , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P41RR001209

July 1, 2008 - June 30, 2012 - Biomimetic Properties of Cementum and Its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R00DE018212

July 15, 2010 - July 14, 2011 - High Resolution Non-Invasive Imaging of Oral and Craniofacial Tissues , Principal Investigator . Sponsor: NIH, Sponsor Award ID: S10RR026645

July 1, 2007 - June 30, 2008 - Biomimetic Properties of Cementum and its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K99DE018212

June 19, 2020 - June 22, 2023 - Functional Competance of Dentoalveolar Joints in Vertebrates , Principal Investigator . Sponsor: NIH/NIDCR, Sponsor Award ID: 2 R01 DE022032 06A1
July 11, 2016 - June 30, 2019 - Multiscale form and function can predict renal biomineralization , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21DK109912
February 9, 2012 - January 31, 2017 - Load-mediated Adaptation of the Bone-PDL-Tooth Complex in Vertebrates , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DE022032
March 1, 1980 - February 28, 2015 - A Synchroton Radiation Structural Biology Resource , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P41RR001209
July 1, 2008 - June 30, 2012 - Biomimetic Properties of Cementum and Its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R00DE018212
July 15, 2010 - July 14, 2011 - High Resolution Non-Invasive Imaging of Oral and Craniofacial Tissues , Principal Investigator . Sponsor: NIH, Sponsor Award ID: S10RR026645
July 1, 2007 - June 30, 2008 - Biomimetic Properties of Cementum and its Interfaces , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K99DE018212

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