The UCSF Department of Urology is committed to offering the highest quality urologic care and innovative research programs. The following studies are taking place in our department's clinical trials office. If interested to join any of the studies, please call 415-353-7348 or email: [email protected] or [email protected]
(Your participation in a clinical trial is voluntary. The information you provide will be confidential, and individual information will not be released.)
Exercise may delay prostate cancer progression
UCSF investigators have reported that brisk walking or other aerobic exercise and intake of specific foods may delay or deter progression of prostate cancer. To expand on these exciting results, we are conducting research to examine whether personalized exercise and diet programs alter prostate cancer biology or reduce the risk of progression.
AS Exercise RCT: A Randomized Clinical Trial of Exercise versus Usual Care among Men Opting for Active Surveillance for Prostate Cancer
We are conducting a clinical trial of tailored exercise for men choosing active surveillance for early stage/low grade prostate cancer. This study is open to men who are on Active Surveillance for localized prostate cancer. Participants assigned to the intervention will receive a four-month home-based personalized exercise prescription, free exercise coaching, and a heart-rate monitor. Participants will be asked to come on site 2-3 times; those who complete all study assessments may earn up to $500.
AS Exercise Observational Study: An Observational Study of Exercise among Men Opting for Active Surveillance for Prostate Cancer
We are conducting a study of cardiopulmonary fitness among men choosing active surveillance for early stage/low grade prostate cancer. This study is open to men who are on Active Surveillance for localized prostate cancer. Participants who complete the one-time study assessment will receive $100.
CHAMP: A randomized Controlled trial of High-intensity Aerobic and resistance exercise for Metastatic Prostate cancer
We are conducting a clinical trial of tailored exercise for men with metastatic castrate-resistant prostate cancer. This study will enroll prostate cancer patients with metastases while on standard hormonal therapy but with little to no symptoms. Participants assigned to an intervention group (aerobic or resistance exercise) will receive a three-month personalized exercise prescription and can opt for supervised exercise with an exercise specialist or remote exercise at a local gym (with remote monitoring by an exercise specialist). All participants will receive a consultation with an exercise specialist; those who complete all study assessments may earn up to $100.
Prostate 8 Study - II: A Randomized Controlled Trial of Diet & Exercise Interventions among Men with Prostate Cancer – II
Our UCSF research team has developed diet and exercise programs specifically geared toward men with prostate cancer. The purpose of this study is to determine whether a 2-year wellness program focused on diet and exercise improves biological, clinical, and quality of life outcomes in men choosing surgery as primary treatment for prostate cancer. Men will enroll 6-8 weeks prior to radical prostatectomy and are followed for 2 years. If you participate in this study you will be randomly assigned to one of four study groups that will receive different educational and supportive tools. At different points in the study, all men will receive print educational materials about the benefits of exercise and diet for men with prostate cancer, a personalized lifestyle report, heart rate monitor and resistance bands to use during exercise, and a 9-week text messaging program focused on your recovery after radical prostatectomy surgery. Those who complete all study assessments may earn up to $250.
(Please call us or check back for further information)
A new digital cohort for individuals with prostate, bladder or colorectal cancer – an observational study consisting of surveys about lifestyle and quality of life, with options to donate digital app data (e.g., Fitbit)
Please consider volunteering for research and tell your friends!
Main Clinical Research Coordinator Supervisor: Imelda Tenggara
In collaboration with: UCSF Depts. of Urology, Epidemiology & Biostatistics, Pathology, Medicine (including Division of Hematology/Oncology), Physical Therapy and Rehabilitation Science, Orthopedic Surgery, Radiation Oncology; and Urologic Clinical and Translational Science staff (Dept. of Urology); Children’s Hospital Oakland Research Institute; UCSF Osher Center for Integrative Medicine; & the UCSF Helen Diller Family Comprehensive Cancer Center. External Collaborators: Oregon Health Sciences University, Memorial Sloan Kettering Cancer Center, Harvard T.H. Chan School of Public Health, & Edith Cowan University (Australia).
Acknowledgements: National Institutes of Health/National Cancer Institute, Department of Defense, Helen Diller Family Chair in Population Science for Urologic Cancer, Steven & Christine Burd Safeway Distinguished Professorship, GenomeDx, Movember Foundation, Prostate Cancer Foundation.
We are indebted to all the study participants! Thank You!
Interested to make a donation to our research team?
Gifts can be made at makeagift.ucsf.edu/urology (Click on the blue “direct your gift to a specific area” button; click “other” and type in “Dr. Chan Lifestyle Research”) or mail to:
C/O Dawn Mitchell
P.O. Box 45339
San Francisco, CA 94145-0339
Note Dr. Chan Lifestyle Research on memo of check